2019

Medical Treatment

• Uchinami Y, Suzuki R, Katoh N, Taguchi H, Yasuda K, Miyamoto N, Ito YM, Shimizu S, Shirato H. Impact of organ motion on volumetric and dosimetric parameters in stomach lymphomas treated with intensity-modulated radiotherapy. J Appl Clin Med Phys. 2019 Aug;20(8):78-86.
• Prayongrat A, Kobashi K, Ito YM, Katoh N, Tamura M, Dekura Y, Toramatsu C, Khorprasert C, Amornwichet N, Alisanant P, Shirato H, Shimizu S. The normal tissue complication probability model-based approach considering uncertainties for the selective use of radiation modality in primary liver cancer patients. Radiother Oncol. 2019 Jun;135:100-106.
• Hashimoto T, Shimizu S, Takao S, Terasaka S, Iguchi A, Kobayashi H, Mori T, Yoshimura T, Matsuo Y, Tamura M, Matsuura T, Ito YM, Onimaru R, Shirato H. Clinical experience of craniospinal intensity-modulated spot-scanning proton therapy using large fields for central nervous system medulloblastomas and germ cell tumors in children, adolescents, and young adults. J Radiat Res. 2019 Jul 1;60(4):527-537.
• Dekura Y, Nishioka K, Hashimoto T, Miyamoto N, Suzuki R, Yoshimura T, Matsumoto R, Osawa T, Abe T, Ito YM, Shinohara N, Shirato H, Shimizu S. The urethral position may shift due to urethral catheter placement in the treatment planning for prostate radiation therapy. Radiat Oncol. 2019 Dec 12;14(1):226.
• Yoshimura T, Shimizu S, Hashimoto T, Nishioka K, Katoh N, Inoue T, Taguchi H, Yasuda K, Matsuura T, Takao S, Tamura M, Ito YM, Matsuo Y, Tamura H, Horita K, Umegaki K, Shirato H. Analysis of treatment process time for real-time-image gated-spot-scanning proton-beam therapy (RGPT) system. J Appl Clin Med Phys. 2019 Dec 30.

Medical physics

• Takayanagi T, Uesaka T, Kitaoka M, Unlu MB, Umegaki K, Shirato H, Xing L, Matsuura T. A novel range-verification method using ionoacoustic wave generated from spherical gold markers for particle-beam therapy: a simulation study. Sci Rep. 2019 Mar 8;9(1):4011.
• Ueno K, Matsuura T, Hirayama S, Takao S, Ueda H, Matsuo Y, Yoshimura T, Umegaki K. Physical and biological impact of collimator-scattered protons in spot-scanning proton therapy. J Appl Clin Med Phys. 2019 May 4;20:7:48-57.
• Nomura Y, Xu Q, Shirato H, Shimizu S, Xing L. Projection-domain scatter correction for cone beam computed tomography using a residual convolutional neural network. Med Phys. 2019 Jul;46(7):3142-3155.
• Miyamoto N, Maeda K, Abo D, Morita R, Takao S, Matsuura T, Katoh N, Umegaki K, Shimizu S, Shirato H. Quantitative evaluation of image recognition performance of fiducial markers in real-time tumor-tracking radiation therapy. Phys Med. 2019 Sep;65:33-39.
• Suzuki R, Miyamoto N, Takao S, Shimizu S.[Department of Medical Physics, Hokkaido University Hospital]. Igaku Butsuri. 2019;39(2):54-56.
• Kwon J, Rajamahendiran RM, Virani NA, Kunjachan S, Snay E, Harlacher M, Myronakis M, Shimizu S, Shirato H, Czernuszewicz TJ, Gessner R, Berbeco R. Use of 3-D Contrast-Enhanced Ultrasound to Evaluate Tumor Microvasculature After Nanoparticle-Mediated Modulation. Ultrasound Med Biol. 2020 Feb;46(2):369-376.
• Nomura Y, Xu Q, Peng H, Takao S, Shimizu S, Xing L, Shirato H. Modified fast adaptive scatter kernel superposition (mfASKS) correction and its dosimetric impact on CBCT-based proton therapy dose calculation. Med Phys. 2020 Jan;47(1):190-200.

Radiobiology

• Wu PH, Onodera Y, Recuenco FC, Giaccia AJ, Le QT, Shimizu S, Shirato H, Nam JM. Lambda-Carrageenan Enhances the Effects of Radiation Therapy in Cancer Treatment by Suppressing Cancer Cell Invasion and Metastasis through Racgap1 Inhibition. Cancers (Basel). 2019 Aug 16;11(8).
• Wu PH, Opadele AE, Onodera Y, Nam JM. Targeting Integrins in Cancer Nanomedicine: Applications in Cancer Diagnosis and Therapy. Wu PH, Opadele AE, Onodera Y, Nam JM.Cancers (Basel). 2019 Nov 13;11(11). Review.

Joint research / Others

• Kikuchi Y, Naya M, Oyama-Manabe N, Manabe O, Sugimori H, Kudo K, Kato F, Aikawa T, Tsutsui H, Tamaki N, Shirato H. Assessment of Coronary Flow Velocity Reserve in the Left Main Trunk Using Phase-contrast MR Imaging at 3T: Comparison with ¹⁵O-labeled Water Positron Emission Tomography. Magn Reson Med Sci. 2019 Apr 10;18(2):134-141.
• Mizumachi T, Kano S, Homma A, Akazawa M, Hasegawa C, Shiroishi Y, Okamoto C, Kumagai S, Nishimura M, Takasaki H, Takeda H, Yasuda K, Minatogawa H, Dekura Y, Onimaru R, Shirato H, Fukuda S.[A Nutritional Supplement with a High Blend Ratio of ω-3 Fatty Acids(Prosure®) Reduces Severe Oral Mucositis and Body Weight Loss for Head and Neck Cancer Patients Treated with Chemoradiotherapy]. Gan To Kagaku Ryoho. 2019 Apr;46(4):685-689. Japanese.
• Mazaki Y, Higashi T, Onodera Y, Nam JM, Hashimoto A, Hashimoto S, Horinouchi T, Miwa S. Endothelin type B receptor interacts with the 78-kDa glucose-regulated protein. FEBS Lett. 2019 Mar;593(6):644-651.
• Fujima N, Shimizu Y, Yoshida D, Kano S, Mizumachi T, Homma A, Yasuda K, Onimaru R, Sakai O, Kudo K, Shirato H. Machine-Learning-Based Prediction of Treatment Outcomes Using MR Imaging-Derived Quantitative Tumor Information in Patients with Sinonasal Squamous Cell Carcinomas: A Preliminary Study. Cancers (Basel). 2019 Jun 10;11(6).
• Kato F, Kudo K, Yamashita H, Baba M, Shimizu A, Oyama-Manabe N, Kinoshita R, Li R, Shirato H. Predicting metastasis in clinically negative axillary lymph nodes with minimum apparent diffusion coefficient value in luminal A-like breast cancer. Breast Cancer. 2019 Sep;26(5):628-636.
• Morita R, Abo D, Sakuhara Y, Soyama T, Katoh N, Miyamoto N, Uchinami Y, Shimizu S, Shirato H, Kudo K. Percutaneous insertion of hepatic fiducial true-spherical markers for real-time adaptive radiotherapy. Minim Invasive Ther Allied Technol. 2019 Sep 13:1-10.
• Ishikawa H, Tsuji H, Murayama S, Sugimoto M, Shinohara N, Maruyama S, Murakami M, Shirato H, Sakurai H. Particle therapy for prostate cancer: The past, present and future. Int J Urol. 2019 Oct;26(10):971-979. Review.
• Annan DA, Maishi N, Soga T, Dawood R, Li C, Kikuchi H, Hojo T, Morimoto M, Kitamura T, Alam MT, Minowa K, Shinohara N, Nam JM, Hida Y, Hida K. Carbonic anhydrase 2 (CAII) supports tumor blood endothelial cell survival under lactic acidosis in the tumor microenvironment. Cell Commun Signal. 2019 Dec 17;17(1):169.
• Watanabe S, Inoue T, Okamoto S, Magota K, Takayanagi A, Sakakibara-Konishi J, Katoh N, Hirata K, Manabe O, Toyonaga T, Kuge Y, Shirato H, Tamaki N, Shiga T. Combination of FDG-PET and FMISO-PET as a treatment strategy for patients undergoing early-stage NSCLC stereotactic radiotherapy. EJNMMI Res. 2019 Dec 4;9(1):104.
• Shimizu Y, Kudo K, Kameda H, Harada T, Fujima N, Toyonaga T, Tha KK, Shirato H. Prediction of Hypoxia in Brain Tumors Using a Multivariate Model Built from MR Imaging and ¹⁸F-Fluorodeoxyglucose Accumulation Data. Magn Reson Med Sci. 2019 Oct 15.
• Miyata H, Osawa T, Abe T, Kikuchi H, Matsumoto R, Maruyama S, Nishioka K, Shimizu S, Hashimoto T, Shirato H, Shinohara N. The updated outcomes of bladder-preserving trimodal therapy using a real-time tumor-tracking radiotherapy system for patients with muscle-invasive bladder cancer. Jpn J Clin Oncol. 2020 Jan 19. pii: hyz211.

Books and General remarks

• Shirato H: “Research and Development of Helium and Proton Hybrid Beam Therapy” Science Impact Ltd Volume 2019, Number 4, April 2019, pp. 40-42(3) Publisher: Science Impact Ltd